Plasmodium falciparum homologue of the genes for Plasmodium vivax and Plasmodium yoelii adhesive proteins, which is transcribed but not translated.

نویسندگان

  • H M Taylor
  • T Triglia
  • J Thompson
  • M Sajid
  • R Fowler
  • M E Wickham
  • A F Cowman
  • A A Holder
چکیده

The 235-kDa family of rhoptry proteins in Plasmodium yoelii and the two reticulocyte binding proteins of P. vivax comprise a family of proteins involved in host cell selection and erythrocyte invasion. Here we described a member of the gene family found in P. falciparum (PfRH3) that is transcribed in its entirety, under stage-specific control, with correct splicing of the intron, but appears not to be translated, probably due to two reading frameshifts at the 5' end of the gene.

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عنوان ژورنال:
  • Infection and immunity

دوره 69 6  شماره 

صفحات  -

تاریخ انتشار 2001